Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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556
Thermo Scientific Chemicals Raloxifene hydrochloride
CAS: 82640-04-8 Molecular Formula: C28H27NO4S·HCl
| CAS | 82640-04-8 |
|---|---|
| Molecular Formula | C28H27NO4S·HCl |
557
| CAS | 1370261-96-3 |
|---|---|
| Molecular Formula | C19H23N9O |
558
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Thermo Scientific Chemicals Chlorpropham
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Thermo Scientific Chemicals Chlorpropham
CAS: 101-21-3 Molecular Formula: C10H12ClNO2
| CAS | 101-21-3 |
|---|---|
| Molecular Formula | C10H12ClNO2 |
559
Tocris Bioscience™ Biotin-NAD+
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Biotinylated-NAD+; substrate for ADP-ribosylation
560
Tocris Bioscience™ BAY 593
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Geranylgeranyltransferase-I (GGTase-I) inhibitor
561
Tocris Bioscience™ Janelia Fluor™ 646b, NHS ester
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Blinking fluorescent dye (Reactive group: NHS ester). Application: super resolution microscopy (SRM) including SMLM
562
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Thermo Scientific Chemicals Rofecoxib
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Thermo Scientific Chemicals Rofecoxib
CAS: 162011-90-7 Molecular Formula: C17H14O4S Molecular Weight (g/mol): 314.36 InChI Key: RZJQGNCSTQAWON-UHFFFAOYSA-N IUPAC Name: 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one SMILES: CS(=O)(=O)C1=CC=C(C=C1)C1=C(C(=O)OC1)C1=CC=CC=C1
| CAS | 162011-90-7 |
|---|---|
| Molecular Weight (g/mol) | 314.36 |
| SMILES | CS(=O)(=O)C1=CC=C(C=C1)C1=C(C(=O)OC1)C1=CC=CC=C1 |
| IUPAC Name | 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one |
| InChI Key | RZJQGNCSTQAWON-UHFFFAOYSA-N |
| Molecular Formula | C17H14O4S |
563
Tocris Bioscience™ PSEM 89S
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PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
| Target | Pharmacologically Selective Effector Molecules/PSEM |
|---|---|
| CAS | 1336913-03-1 |
| Purity | 98% |
| Chemical Name or Material | N-(3 S)-1-Azabicyclo[2.2.2 ]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H22N2O3.CF3CO2H |
| Formula Weight | 404.38 |
564
Tocris Bioscience™ ARN 11391
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Potentiator of the IP3-gated calcium channel ITPR1
| Target | IP3R1 |
|---|---|
| CAS | 1214569-31-9 |
| Purity | 0.98 |
| Chemical Name or Material | 2-Ethyl-4,5,6,7-tetrahydro-N-[2-[(tetrahydro-2 H-pyran-2-yl)methoxy]phenyl]-2 H-indazole-3-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H29N3O3 |
565
Tocris Bioscience™ PSEM 308 hydrochloride
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Small and Specialty Supplier Partner
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PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
| Target | Pharmacologically Selective Effector Molecules/PSEM |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 5-Methyl-5,8,9,10,11 A,12-hexahydro-4 H-8,11-ethanopyrido[3 ',2 ':3,4 ]diazepino[6,7,1-hi]indole hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H21N3.HCl |
| Formula Weight | 303.83 |
566
Tocris Bioscience™ FSEN 1
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Induces ferroptosis; inhibits FSP1
| Target | Ferroptosis Inhibitors |
|---|---|
| CAS | 862808-01-3 |
| Purity | 0.98 |
| Chemical Name or Material | 3-(4-Bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H22BrN5OS |
567
Tocris Bioscience™ BI 01383298
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Potent and selective SLC13A5 (Na+/citrate cotransporter) inhibitor
| CAS | 2227549-00-8 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 1-[(3,5-Dichlorophenyl)sulfonyl]-N-[(4-fluorophenyl)methyl]-4-piperidinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H19Cl2FN2O3S |
| Formula Weight | 445.34 |
568
Tocris Bioscience™ BDY FL VH032
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High-affinity VHL fluorescent probe for TR-FRET and FP assays
569
Tocris Bioscience™ AA 147
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ER proteostasis regulator
| CAS | 393121-74-9 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-(2-Hydroxy-5-methylphenyl)benzenepropanamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C16H17NO2 |
| Formula Weight | 255.31 |
570
Tocris Bioscience™ DCLK1-IN-1
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Potent and selective doublecortin like kinase 1/2 (DCLK1/2) inhibitor; orally bioavailable